Keeping Pictus Catfish involves providing a large, well-filtered tank (50+ gallons, ideally 150L+) with sand substrate, hiding spots, and a current, as they are active, social bottom-dwellers, feeding sinking pellets and meaty foods, and maintaining stable water parameters (75-82°F, pH 7.0-7.5), while being mindful they might eat very small tankmates due to their scavenging nature.